The San Francisco 49ers are no strangers to success, but the storied franchise has a chance to get off to a better start than it has in recent years.
With a win Thursday night against the New York Giants, the 49ers will have just their second 3-0 opening in 25 years, with the other such start coming in 2019. Stopping the San Francisco could prove to be a tall task for New York, which will be without Saquon Barkley as the running back recovers from an ankle ailment. The Giants, however, rallied from a 21-point deficit last Sunday to defeat the Arizona Cardinals for their first win of the season.
USA TODAY Sports will have a live breakdown of the game, so check back for more information on all the action:
What time is kickoff for Giants vs. 49ers on ‘Thursday Night Football’?
The Giants and 49ers will kick off at 8:15 p.m. ET on Sept. 21.
NFL STATS CENTRAL: The latest NFL scores, schedules, odds, stats and more.
How can I watch Giants vs 49ers on ‘Thursday Night Football’?
Giants vs. 49ers will be streaming on Amazon Prime Video and will be broadcast in local markets only. The game is also available to stream for free on Fubo.
Giants, 49ers inactives for Thursday night: Brandon Aiyuk out
The 49ers will be without starting wide receiver Brandon Aiyuk due to a shoulder injury that he suffered Week 2 versus the Los Angeles Rams. The 49ers also announced that QB Brandon Allen, OL Nick Zakelj, RB Tyrion Davis-Price, LB Jalen Graham, DL Kalia Davis and CB Ambry Thomas are…
